As far as I know, Calculation is set to Auto or Manual at Workbook level and one can't disable calc in individual worksheets.
Those worksheets "that do not impact the calculations" will in any case be NOT recalculated. So even theoratically turning off calculation in these sheets will not make any difference.
Does this line "each "loop" requires the model to recalculate every worksheet" mean you are using VBA/macro? If yes then try this:
This will stop all calculations, alerts and screen changes, speeding up the code considerably.Code:Sub Test() Application.DisplayAlerts = False Application.ScreenUpdating = False Application.Calculation = xlCalculationManual 'your code here Application.DisplayAlerts = True Application.ScreenUpdating = True Application.Calculation = xlCalculationAutomatic End Sub