Hi Dream,
Yes. Just as an example, this code will put the Date-time stamp in column E of the same row in which a hyperlink is followed:
Private Sub Worksheet_FollowHyperlink(ByVal Target As Hyperlink)
Target.Parent.EntireRow.Cells(1, 5) = Now
End Sub
This is a worksheet event procedure, so must be placed in the worksheet's event code module. To do this, right-click on the worksheet's tab, select View Code, and paste this code into the Code pane.