I'm not sure if you can do it directly, but you can do it indirectly.
For example, in some cell, let's say C17, you could have a formula like this
Then, for your data validation, specify LIST, and specify cell C17 as the source of the list.
Does this make sense ?
If you already have 10 or more "V"s, then the Data Validation list will be blank - you won't be able to input another "V".
If you have 9 or less, the Data Validation list should be "V", allowing you to input another.
If you choose this route, you might want to have another cell that just flags up a message, so that users know the maximum has been reached, for example
Code:
=if(C16=10,"Maximum people on vacation has been reached",if(C16>10,"Maximum people on vacation has been exceeded",""))
Bear in mind that Data Validation will not TOTALLY prevent users inputting another V. For example, they will be able to do it by Cutting and Pasting.