Because M is case sensitive, this formula in a custom column will tell you if the string in Column1 contains one of the uppercased letters in the curly-bracket-range:
Text.PositionOfAny([Column1], {"A".."Z"})=-1
So if none of the capital letters is found, Text.PositionOfAny returns -1.
You can add special characters like this: {"A".."Z", "Ü"}